Multimodal MRI Neuroimaging Biomarkers for Cognitive Normal Adults, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease
Patterns of GMV loss in MCI and normal aging. Average slopes of RAVENS maps for normal (a) and MCI (b) groups. The red-yellow color indicates greater volume loss. Bottom row: difference between the two groups; blue/green are regions in which MCI subjects showed higher rate of gray matter decrease. (c) Red/yellow colors reflect an increase of periventricular small vessel disease, which appears gray in T1-weighted images and is segmented as gray matter. The color bars display estimated regression coefficients and are defined by the following numbers, all in mm3/year (per voxel in the template space): , , , , , and (adapted with permission from ).
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