Genetics of Cerebral Vasospasm

Table 1

Summary of prognostic genes in cerebral vasospasm.

Gene	Reference	𝑁	Finding
eNOS	[19]	141	T-786C promoter → clinical/angiographic and/or TCD vasospasm
eNOS	[20]	51	T-786C SNP → symptomatic/asymptomatic angiographic vasospasm
eNOS	[21]	136	No relationship
eNOS	[22]	347	T-786C SNP → angiographic vasospasm
eNOS	[23]	77	T-786C SNP → angiographic vasospasm
Hp	[24]	32	Hp 2 allele → angiographic and/or TCD vasospasm
PAI-1	[25]	126	4G allele → DCI and poor 3-month GOS
PAI-1	[26]	183	No relationship b/w allele and 1-year GOS-E
ApoE	[27]	206	ApoE4 allele → poor GOS
ApoE	[28]	101	−219T→ clinical and TCD vasospasm
RyR1	[29]	46	GT c.6178G→T → symptomatic vasospasm
CBS	[30]	87	699CT and TT → angiographic vasospasm, but no increase in delayed cerebral ischemia. 1080TT → DCI