Clinical Study
Apathy in Parkinson’s Disease: An Electrophysiological Study
Table 1
Correlation between the apathy score (during OFF and ON periods) and electrophysiological cognitive, thymic, and motor data.
| Data | Apathy score (OFF period) | Apathy score (ON period) | | | | |
| Electrophysiological | | | | | P300 amplitude in Cz |
0.008 | −0.541 | 0.5135 | 0.133 | P300 amplitude in Pz | 0.0279 | −0.449 | 0.2911 | 0.215 | P300 average amplitude in Cz | 0.0293 | −0.445 | 0.5633 | 0.118 | P300 average amplitude in Fz | 0.0374 | −0.425 | 0.8874 | −0.029 | P300a amplitude in Fz | 0.0707 | −0.369 | 0.0014 | −0.668 | Cognitive | | | | | Verbal fluency (animals) | 0.0153 | −0.495 | 0.1608 | −0.286 | Verbal fluency (letter M) | 0.0009 | −0.679 | 0.0083 | −0.539 | Verbal fluency (boy + fruit names) | 0.0159 | −0.492 | 0.4786 | −0.145 | Stroop test (SR-SP) | 0.1795 | −0.274 | 0.1769 | −0.276 | Wisconsin (number of series) | 0.0098 | −0.527 | 0.0037 | −0.593 | Wisconsin (number of mistakes) | 0.0037 | 0.592 | 0.0019 | 0.633 | Wisconsin (perseveration percentage) | 0.1097 | 0.327 | 0.0342 | 0.4322 | Thymic | | | | | HAD (depression) | 0.0003 | 0.739 | 0.0015 | 0.647 | HAD (anxiety) | 0.0532 | 0.0532 | 0.3552 | 0.189 | Motor | | | | | UPDRS III (total score) | 0.1051 | 0.331 | 0.012 | 0.513 | UPDRS III (axial score) | 0.0594 | 0.385 | 0.0201 | 0.474 |
|
|
: probability; : coefficient of correlation.
|