Clinical Study

Apathy in Parkinson’s Disease: An Electrophysiological Study

Table 1

Correlation between the apathy score (during OFF and ON periods) and electrophysiological cognitive, thymic, and motor data.

DataApathy score (OFF period)Apathy score (ON period)

Electrophysiological
 P300 amplitude in Cz 0.0080.541 0.51350.133
 P300 amplitude in Pz0.02790.449 0.29110.215
 P300 average amplitude in Cz0.02930.445 0.56330.118
 P300 average amplitude in Fz0.03740.425 0.88740.029
 P300a amplitude in Fz0.07070.369 0.00140.668
Cognitive
 Verbal fluency (animals)0.01530.495 0.16080.286
 Verbal fluency (letter M)0.00090.679 0.00830.539
 Verbal fluency (boy + fruit names)0.01590.492 0.47860.145
 Stroop test (SR-SP)0.17950.274 0.17690.276
 Wisconsin (number of series)0.00980.527 0.00370.593
 Wisconsin (number of mistakes)0.00370.592 0.00190.633
 Wisconsin (perseveration percentage)0.10970.327 0.03420.4322
Thymic
 HAD (depression)0.00030.739 0.00150.647
 HAD (anxiety)0.05320.0532 0.35520.189
Motor
 UPDRS III (total score)0.10510.331 0.0120.513
 UPDRS III (axial score)0.05940.385 0.02010.474

: probability; : coefficient of correlation.