Clinical Study
Apathy in Parkinson’s Disease: An Electrophysiological Study
Table 2
Characteristics distinguishing apathetic from nonapathetic patients during OFF period.
| Data | Average in apathetic patients () | Average in nonapathetic patients () | | |
| General | | | | | Age (years) | 67.4 | 61.9 | 0.0301 | −2.168 | Electrophysiological | | | | | Average P300a amplitude in Fz (V) | 14.0 | 23.1 | 0.0592 | −1.886 | Cognitive | | | | | Verbal fluency (animals) | 14.8 | 20.8 | 0.0113 | −2.533 | Verbal fluency (letter M) | 5.6 | 12.9 | 0.0017 | −3.146 | Wisconsin (number of series) | 2.8 | 4.7 | 0.0144 | −2.448 | Wisconsin (number of mistakes) | 23.6 | 9.3 | 0.002 | −3.085 | Wisconsin (perseveration percentage) | 36.5 | 19.3 | 0.0272 | −2.209 | Stroop (SR-SP) | −4.3 | 0.4 | 0.1831 | −1.331 | Apathy (Starkstein) | 16.2 | 6.8 | 0.001 | −4.174 | Thymic | | | | | HAD (depression) | 8.5 | 3.3 | 0.0002 | −3.68 | HAD (anxiety) | 10.5 | 8.3 | 0.0613 | −1.872 | Motor | | | | | UPDRS III (total score) | 28.8 | 23.9 | 0.1561 | −1.418 | UPDRS III (axial score) | 14.4 | 9.267 | 0.0226 | −2.28 |
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: probability; : coefficient of correlation.
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