Clinical Study
Apathy in Parkinson’s Disease: An Electrophysiological Study
Table 3
Characteristics distinguishing apathetic from nonapathetic patients during ON period.
| | Data | Average in apathetic patients
() | Average in nonapathetic patients
() | | |
| | General | | | | | | Age (years) | 67.4 | 63.3 | 0.1957 | −1.274 | | Electrophysiological | | | | | | Average P300a amplitude in Fz (V) | 8.6 | 21.6 | 0.0032 | −2.950 | | N200 latency in Cz (ms) | 273.4 | 239.6 | 0.0295 | −2.177 | | Cognitive | | | | | | Verbal fluency (animals) | 17.2 | 19.6 | 0.4142 | −0.816 | | Verbal fluency (letter M) | 6.2 | 10 | 0.0509 | −1.952 | | Wisconsin (number of series) | 2.8 | 4.8 | 0.0171 | −2.385 | | Wisconsin (number of errors) | 21.0 | 10.8 | 0.0224 | −2.284 | | Wisconsin (perseveration percentage) | 38.0 | 18.7 | 0.0636 | −1.855 | | Stroop (SR-SP) | −2.1 | −1.8 | 0.8385 | −0.204 | | Apathy (Starkstein) | 17.6 | 7.0 | 0.0007 | −3.405 | | Thymic | | | | | | HAD (depression) | 8.6 | 3.9 | 0.0198 | −2.330 | | HAD (anxiety) | 11 | 7.3 | 0.0181 | −2.363 | | Motor | | | | | | UPDRS III (total score) | 11.6 | 8.3 | 0.1138 | −1.726 | | UPDRS III (axial score) | 6.2 | 3.8 | 0.0931 | −1.679 |
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: probability; : coefficient of correlation.
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