Research Article
Aortic Stiffness Is Related to the Ischemic Brain Injury Biomarker N-Methyl-D-aspartate Receptor Antibody Levels in Aortic Valve Replacement
Table 3
Simple and multiple logistic regression analysis to identify variables that independently predict patients with high NR2Ab (NR2Ab 1.8 ng/mL cut-off).
| | Predictors | NR2Ab 1.8 ng/mL cut-off | | OR (95%CI) | -value |
| | Simple logistic regression | | PWV value | 1.29 (0.97–1.71) | 0.08 | | PWV cut-off | 6.93 (1.91–25.17) | <0.01 | | Age | 1.0 (0.93–1.01) | 0.96 | | Gender (male) | 0.18 (0.05–0.67) | 0.01 | | DM | 1.63 (0.33–8.01) | 0.54 | | Smoking | 0.94 (0.33–2.65) | 0.92 | | BMI (kg/m2) | 0.88 (0.79–1.02) | 0.09 | | MAP (mmHg) | 0.97 (0.92–1.02) | 0.31 | | Cholesterol (mmol/L) | 1.63 (0.84–3.19) | 0.14 | | EuroSCORE (Logistic) | 1.09 (0.95–1.25) | 0.21 | | AVA (cm2) | 0.35 (0.01–6.98) | 0.49 | | AVMG (mmHg) | 0.99 (0.64–1.03) | 0.69 | | AVPG (mmHg) | 1.0 (0.97–1.02) | 0.96 | | EF | 1.0 (0.96–1.05) | 0.72 |
| | Multiple logistic regression (Model 1) | | PWV value | 1.4 (0.94–2.06) | 0.09 | | Age | 0.95 (0.86–1.05) | 0.32 | | Gender (male) | 0.21 (0.05–0.79) | 0.02 |
| | Multiple logistic regression (Model 2) | | PWV cut-off | 7.23 (1.74–30.1) | <0.01 | | Age | 0.98 (0.91–1.06) | 0.66 | | Gender (male) | 0.19 (0.04–0.8) | 0.02 |
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Values are shown as odd ratio (OR) and value; bold values indicate statistical significance. Abbreviations: AVA, aortic valve area; AVMG, aortic valve mean gradient; AVPG, aortic valve peak gradient; BMI, body mass index; DM, diabetes mellitus; EF, Ejection fraction; MAP, mean arterial blood pressure; NR2Ab, N-methyl-D-aspartate (NMDA) receptor antibodies; PWV, pulse wave velocity.
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