Deletion of Ovarian Hormones Induces a Sickness Behavior in Rats Comparable to the Effect of Lipopolysaccharide

Figure 3

Comparison of peripheral crossing number (a), the time spent in peripheral zone (b), and the traveled distance in peripheral zone (c) in the open field test between four groups. Data are expressed as mean ± SEM ( in each group). The number of crossing, the time spent, and the traveled distance in the peripheral zone in the OVX and Sham-LPS group groups were lower than that of the Sham group (). The peripheral crossing number by the animals of OVX-LPS group was not different than that of OVX group. There was also no significant differences between OVX-LPS and OVX group in the time spent in peripheral zone and peripheral crossing number; however, the traveled distance in the peripheral zone by the animals of OVX-LPS group was lower than that of OVX group ().

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