Hypobaric Hypoxia Imbalances Mitochondrial Dynamics in Rat Brain Hippocampus

Table 3

Effect of HH on specific activity of respiratory complex enzymes.

Serial number	Mitochondrial complexes of electron transport chain	Cntrl	3 dHH	7 dHH	14 dHH	21 dHH	28 dHH
1	Complex I activity; (mole NADH oxidised/mg protein)	76.26 ± 9.2	70.92 ± 6.6	64.83 ± 5.7	72.13 ± 4.2	75.15 ± 6.2	75.16 ± 8.1
2	Complex II activity; (succinate-CoQ reductase activity/min/mg protein)	51.28 ± 2.7	45.81 ± 3.1	42.05 ± 2.6	48.18 ± 1.5	50.57 ± 2.7	50.78 ± 3.8
3	Complex III activity; (cytochrome c-CoQ reductase activity/min/mg protein)	85.72 ± 3.1	77.26 ± 6.6	74.91 ± 7.2	81.42 ± 2.4	83.43 ± 4.1	84.35 ± 5.6
4	Complex IV activity; (nmol reduced cytochrome c oxidized/min/mg protein)	58.44 ± 3.1	56.82 ± 3.5	50.94 ± 3.7	53.23 ± 2.2	55.56 ± 1.5	57.24 ± 2.7

and denotes and respectively compare to Cntrl.