Protective Effect of PPARγ Agonists on Cerebellar Tissues Oxidative Damage in Hypothyroid Rats

Figure 1

The effects of PTU, Vit E, pioglitazone, and rosiglitazone on serum thyroxine concentrations. Data are presented as mean ± SEM; . versus group I, and versus group II, and versus group III. The data from different treatment groups were compared by using one way ANOVA followed by post hoc LSD test. Group I (control), the animals received drinking water; group II, the animals received 0.05% propylthiouracil (PTU) in drinking water; besides PTU, the animals in groups III, IV, V, VI, and VII were injected with 20 mg/kg vitamin E (vit E), 10 or 20 mg/kg pioglitazone, and 2 or 4 mg/kg rosiglitazone, respectively.