BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal
Table 2
Baseline characteristics of volunteers according to the motor nerve. The values in the column of the motor nerves outside the small bracket are the count per total and those inside the bracket are the percentage.
Motor nerves
Variables
Peripheral nerve function
Number of nerves involved
Normal ()
Abnormal ()
value
<2 ()
≥2 ()
value
Age (years)
40.0 (13.0)
41.0 (13.0)
0.626
39.0 (13.0)
42.0 (22.0)
0.109
Gender (female)
21 (42)
24 (48)
1.000
31 (62)
14 (28)
0.304
Socioeconomic status
0.233
0.454
Lower
1 (2)
2 (4)
1 (2)
2 (4)
Lower middle
3 (6)
10 (20)
9 (18)
4 (8)
Upper lower
14 (28)
11 (22)
19 (38)
6 (12)
Upper middle
5 (10)
4 (8)
7 (14)
2 (4)
Alcohol consumer
2 (4)
2 (4)
1.000
4 (8)
0
0.566
Smoker
2 (4)
2 (4)
1.000
3 (6)
1 (2)
1.000
Exercise
6 (12)
8 (16)
0.781
10 (20)
4 (8)
1.000
Obesity in family
2 (4)
3 (6)
1.000
4 (8)
1 (2)
1.000
Diabetes in family
0
1 (2)
1.000
1 (2)
0
1.000
Hypertension history
0.235
0.013
None
16 (69.6)
18 (66.7)
27 (75)
7 (50.0)
<1 to 5 years
7 (30.4)
6 (22.2)
9 (25)
4 (28.6)
5 to >10 years
0
3 (11.1)
0
3 (21.4)
Time of weight gained
0.275
0.008
<1 to 5 years
15 (65.2)
16 (59.3)
23 (63.9)
8 (57.1)
5 to 10 years
4 (17.4)
3 (11.1)
6 (16.7)
1 (7.1)
10 to 15 years
4 (17.4)
4 (14.8)
7 (19.4)
1 (7.1)
15 to >20 years
0
4 (14.8)
0
4 (28.6)
Height (m)
1.52 (0.06)
1.50 (0.08)
0.384
1.51 (0.06)
1.50 (0.10)
0.356
Weight (kg)
72.78 ± 9.23
76.33 ± 10.62
0.217
74.67 ± 10.34
74.79 ± 9.70
0.971
BMI (kg/m2)
31.33 ± 3.66
33.57 ± 4.10
0.048
32.29 ± 4.04
33.19 ± 4.05
0.485
BMI class
0.188
1.000
Obese-I
8 (34.8)
4 (14.8)
9 (25.0)
3 (21.4)
Obese-II
15 (65.2)
23 (85.2)
27 (75.0)
11 (78.6)
Waist-hip ratio
0.86 ± 0.07
0.88 ± 0.07
0.268
0.87 ± 0.08
0.89 ± 0.05
0.305
Waist-height ratio
0.61 ± 0.06
0.64 ± 0.06
0.050
0.62 ± 0.05
0.65 ± 0.06
0.086
Fasting BGL (mg/dL)
92.37 ± 9.75
100.17 ± 12.29
0.018
95.77 ± 12.63
98.66 ± 9.23
0.442
BGL at 2 h (mg/dL)
114.4 (25.9)
128.1 (39.5)
0.034
121.9 (33.5)
127.85 (39.75)
0.437
Fasting serum insulin
9.96 (4.08)
11.18 (7.96)
0.227
9.98 (5.00)
12.37 (9.60)
0.054
Serum insulin at 2 h
62.2 (43.46)
64.41 (111.59)
0.381
62.68 (68.49)
70.51 (106.23)
0.130
hsCRP
6 (26.1)
9 (33.3)
0.804
10 (27.8)
5 (35.7)
0.733
HOMA-IR
2.07 (1.27)
2.73 (1.87)
0.087
2.19 (1.27)
2.98 (2.37)
0.039
HOMA-IR class
0.189
0.096
<2
11 (47.8)
7 (25.9)
16 (44.4)
2 (14.3)
>2
12 (52.2)
20 (74.1)
20 (55.6)
12 (85.7)
QUICKI
0.34 ± 0.03
0.33 ± 0.02
0.133
0.34 ± 0.02
0.32 ± 0.02
0.049
BGL, blood glucose level; hsCRP, high sensitivity C-reactive protein. Mean ± SD, median (IQR), and significant at .
