BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal

Table 3

Baseline characteristics of volunteers according to the sensory nerve. The values in the column of the sensory nerves outside the small bracket are the count per total and those inside the bracket are the percentage.

	Sensory nerves
Variables	Peripheral nerve function			Number of nerves involved
	Normal ()	Abnormal ()	value	<2 ()	≥2 ()	value
Age (years)	39.5 (15.0)	40.5 (12.0)	0.468	42.0 (14.0)	40.0 (12.0)	0.689
Gender (female)	12 (85.7)	33 (91.7)	0.611	20 (87.0)	25 (92.6)	0.651
Socioeconomic status			0.223			0.381
Lower	1 (7.1)	2 (5.6)		2 (8.7)	1 (3.7)
Lower middle	3 (21.4)	10 (27.8)		6 (26.1)	7 (25.9)
Upper lower	5 (35.7)	20 (55.6)		9 (39.1)	16 (59.3)
Upper middle	5 (35.7)	4 (11.1)		6 (26.1)	3 (11.1)
Alcohol consumer	1 (7.1)	3 (8.3)	1.000	2 (8.7)	2 (7.4)	1.000
Smoker	2 (14.3)	2 (5.6)	0.310	3 (13.0)	1 (3.7)	0.322
Exercise	4 (28.6)	10 (27.8)	1.000	5 (21.7)	9 (33.3)	0.552
Obesity in family	1 (7.1)	4 (11.1)	1.000	1 (4.3)	4 (14.8)	0.357
Diabetes in family	0	1 (2.8)	1.000	0	1 (3.7)	1.000
Hypertension history			0.535			0.754
None	10 (71.4)	24 (66.7)		15 (65.2)	19 (70.4)
<1 to 5 years	4 (28.6)	9 (25.0)		7 (30.4)	6 (22.2)
5 to >10 years	0	3 (8.3)		1 (4.3)	2 (7.4)
Time of weight gained			0.741			0.949
<1 to 5 years	10 (71.4)	21 (58.3)		15 (65.2)	16 (59.3)
5 to 10 years	2 (14.3)	5 (13.9)		3 (13.0)	4 (14.8)
10 to 15 years	1 (7.1)	7 (19.4)		3 (13.0)	5 (18.5)
15 to >20 years	1 (7.1)	3 (8.3)		2 (8.7)	2 (7.4)
Height (m)	1.51 (0.04)	1.50 (0.09)	0.737	1.51 (0.05)	1.50 (0.09)	0.395
Weight (kg)	70.93 ± 7.42	76.17 ± 10.66	0.099	73.22 ± 9.01	75.96 ± 10.90	0.342
BMI (kg/m^2)	31.01 ± 3.20	33.14 ± 4.19	0.093	31.41 ± 3.31	33.50 ± 4.37	0.067
BMI class			0.278			1.000
Obese-I	5 (35.7)	7 (19.4)		6 (26.1)	6 (22.2)
Obese-II	9 (64.3)	29 (80.6)		17 (73.9)	21 (77.8)
Waist-hip ratio	0.89 ± 0.09	0.87 ± 0.06	0.305	0.89 ± 0.08	0.86 ± 0.07	0.231
Waist-height ratio	0.63 ± 0.06	0.63 ± 0.06	0.843	0.63 ± 0.06	0.63 ± 0.06	0.680
Fasting BGL (mg/dL)	95.45 ± 8.81	97.02 ± 12.81	0.676	97.19 ± 10.25	96.06 ± 13.07	0.740
BGL at 2 h (mg/dL)	116.3 (28.15)	124.5 (41.92)	0.280	114.7 (30.8)	125 (39.5)	0.192
Fasting serum insulin	10.27 (5.13)	10.19 (7.69)	0.846	10.10 (7.69)	10.34 (5.73)	0.755
Serum insulin at 2 h	60.77 (33.04)	65.30 (86.27)	0.531	60.83 (29.57)	76.60 (86.85)	0.471
hsCRP	3 (21.4)	12 (33.3)	0.507	5 (21.7)	10 (37.0)	0.386
HOMA-IR	2.34 (0.95)	2.45 (1.68)	0.923	2.45 (1.93)	2.43 (1.50)	0.668
HOMA-IR class			0.312			0.645
<2	3 (21.4)	15 (41.7)		7 (30.4)	11 (40.7)
>2	11 (78.6)	21 (58.3)		16 (69.6)	16 (59.3)
QUICKI	0.33 ± 0.22	0.34 ± 0.03	0.77	0.33 ± 0.03	0.34 ± 0.03	0.651

Mean ± SD, median (IQR), and significant at .