BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal

Table 4

Baseline characteristics of volunteers according to the total nerve. The values in the column of the mixed nerves outside the small bracket are the count per total and those inside the bracket are the percentage.

	Mixed nerves
Variables	Peripheral nerve function			Number of nerves involved
	Normal ()	Abnormal ()	value	<2 ()	≥2 ()	value
Age (years)	39.5 (13.0)	40.5 (13.0)	0.591	40.0 (14.0)	41.0 (13.0)	0.420
Gender (female)	9 (90)	36 (90)	1.000	12 (80)	33 (94.3)	0.152
Socioeconomic status			0.464			0.740
Lower	1 (10)	2 (5)		1 (6.7)	2 (5.7)
Lower middle	1 (10)	12 (30)		3 (20)	10 (28.6)
Upper lower	5 (50)	20 (50)		7 (46.7)	18 (51.4)
Upper middle	3 (30)	6 (15)		4 (26.7)	5 (14.3)
Alcohol consumer	1 (10.0)	3 (7.5)	1.000	2 (13.3)	2 (5.7)	0.574
Smoker	1 (10)	397.5)	1.000	2 (13.3)	2 (5.7)	0.574
Exercise	3 (30)	11 (27.5)	1.000	3 (20)	11 (31.4)	0.574
Obesity in family	1 (10)	4 (10)	1.000	1 (6.7)	4 (11.4)	1.000
Diabetes in family	0	1 (2.5)	1.000	0	1 (2.9)	1.000
Hypertension history			0.405			0.420
None	6 (60.0)	28 (70.0)		10 (66.7)	24 (68.6)
<1 to 5 years	4 (40.0)	9 (22.5)		5 (33.3)	8 (22.9)
5 to >10 years	0	3 (7.5)		0	3 (8.6)
Time of weight gained			0.203			0.520
<1 to 5 years	9 (90)	22 (55)		11 (73.3)	20 (57.1)
5 to 10 years	0	7 (17.5)		2 (13.3)	5 (14.3)
10 to 15 years	1 (10)	7 (17.5)		2 (13.3)	6 (17.1)
15 to >20 years	0	4 (10)		0	4 (11.4)
Height (m)	1.52 (0.04)	1.50 (0.08)	0.558	1.52 (0.04)	1.50 (0.08)	0.457
Weight (kg)	71.50 ± 7.59	75.50 ± 10.53	0.265	71.53 ± 6.61	76.06 ± 11.04	0.147
BMI (kg/m^2)	30.75 ± 3.17	32.99 ± 4.12	0.116	30.82 ± 2.85	33.28 ± 4.26	0.047
BMI class			0.225			0.471
Obese-I	4 (40)	8 (20)		5 (33.3)	7 (20.0)
Obese-II	6 (60)	32 (80)		10 (66.7)	28 (80)
Waist-hip ratio	0.86 ± 0.08	0.88 ± 0.07	0.433	0.88 ± 0.09	0.87 ± 0.06	0.736
Waist-height ratio	0.62 ± 0.06	0.63 ± 0.06	0.60	0.62 ± 0.06	0.63 ± 0.06	0.384
Fasting BGL (mg/dL)	93.35 ± 7.24	97.39 ± 12.58	0.337	95.65 ± 11.24	96.98 ± 12.11	0.719
BGL at 2 h (mg/dL)	115.85 (30.83)	123.10 (41.92)	0.234	114.70 (31.90)	124.00 (30.90)	0.330
Fasting serum insulin	10.27 (5.78)	10.19 (6.72)	0.896	9.96 (3.85)	10.54 (7.83)	0.433
Serum insulin at 2 h	63.18 (33.04)	63.79 (83.19)	0.693	60.83 (35.73)	64.41 (84.52)	0.357
hsCRP	2 (20)	13 (32.5)	0.702	3 (20)	12 (34.3)	0.502
HOMA-IR	2.34 (1.42)	2.45 (1.66)	0.858	2.22 (1.05)	2.47 (1.78)	0.427
HOMA-IR class			0.730			1.000
<2	3 (30)	15 (37.5)		5 (33.3)	13 (37.1)
>2	7 (70)	25 (62.5)		10 (66.7)	22 (62.9)
QUICKI	0.33 ± 0.03	0.34 ± 0.03	0.869	0.34 ± 0.03	0.33 ± 0.02	0.441

Mean ± SD, median (IQR), and significant at .