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Neurology Research International
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2018
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Article
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Tab 4
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Research Article
Genetic Influences on Cognition in Idiopathic Parkinson’s Disease
Table 4
The mean change in different assessment scales (between 0 and 3 months) of PD patients with different combination of genotypes in Group I and Group II patients.
ApoE
ε
4 carrier/or
ApoE
ε
4 carrier and
P value
MAPT H1/H1
MAPT H1/H1
Mean
SD
Mean
SD
MMSE
0.90
0.85
2.00
1.29
0.048
UPDRSI
-0.95
1.00
-0.71
1.11
0.808
UPDRS total
-4.75
4.96
-6.57
5.0
0.288
PDCRS fronto-
subcortical
2.45
3.41
6.14
3.13
0.019
PDCRS postero-cortical
1.60
2.19
1.71
1.38
0.341
PDCRS total
4.05
4.74
7.86
3.72
0.031
p-value < 0.05 (significant).