Genetic Influences on Cognition in Idiopathic Parkinson’s Disease

Table 4

The mean change in different assessment scales (between 0 and 3 months) of PD patients with different combination of genotypes in Group I and Group II patients.

	ApoE ε4 carrier/or		ApoE ε4 carrier and		P value
	MAPT H1/H1		MAPT H1/H1
	Mean	SD	Mean	SD
MMSE	0.90	0.85	2.00	1.29	0.048
UPDRSI	-0.95	1.00	-0.71	1.11	0.808
UPDRS total	-4.75	4.96	-6.57	5.0	0.288
PDCRS fronto-; subcortical	2.45	3.41	6.14	3.13	0.019
PDCRS postero-cortical	1.60	2.19	1.71	1.38	0.341
PDCRS total	4.05	4.74	7.86	3.72	0.031

  p-value < 0.05 (significant).