Research Article

Serotonin Reuptake Inhibitors in Obstructive Sleep Apnea: Associations in People with and without Epilepsy

Table 1

Baseline characteristics.

-SRI (N=80)
N (%)
+SRI (N=45)
N (%)
χ2p

Gender (male)44 (55)26 (58)0.0900.764
Hypertension21 (26)18 (40)2.5370.111
Diabetes15 (18.75)11 (24)0.5670.451
Congestive Heart Failure 7 (8.75)3 (6.67)0.1700.680
Stroke/TIA15 (18.75)8 (17.78)0.0180.893
COPD/asthma13 (16.25)13 (28.9)2.7930.095
Epilepsy34 (42.5)23 (51)0.8610.353
Focal epilepsy31 (38.75)18 (40)0.0190.891
Generalized epilepsy2 (2.5)2 (4.44)0.3520.553
Undetermined epilepsy1 (1.25)3 (6.67)2.7280.099
Tobacco4 (5)0 (0)2.3240.127
Alcohol0 (0)0 (0)------------
Drug Abuse3 (3.75)1 (2)0.2170.641
Opioids3 (3.75)1 (2)0.2170.641
Benzodiazepines17 (21.25)13 (28.9)0.9210.337
Non-benzodiazepines9 (11.25)4 (9)0.1720.678
AED41 (51.25)32 (71.11)7.8980.048

Mean ± SDMean ± SDCIP

Age (years)57.73±14.4362.51±10.36-9.21-  -0.3660.034
Body Mass Index30.86±6.1330.95±5.91-2.30-2.140.942

SRI: serotonin reuptake inhibitor, TIA: transient ischemic attack, COPD: chronic obstructive pulmonary disease, and AED: antiepileptic drug; : p<0.05.