Validity and Reliability of Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in Indonesia and the Correlation with Quality of Life

Table 3

Association of BICAMS scores with sex, education, depression, age, MS subtype, EDSS, disease duration, and relapse rate.

	Multiple Sclerosis (N=40)			Healthy Control (N=66)
	SDMT	CVLT-II	BVMT-R	SDMT	CVLT-II	BVMT-R
Sex - median (range)
Female	48 (12-69)	56 (25-71)	25 (4-34)	62 (40-110)	64.5(36-77)	31.5(14-36)
Male	30 (8-49)	34 (23-72)	18 (7-32)	64.5(42-92)	60(43-75)	30 (17-36)
p	0.05	0.03	0.15	0.92	0.41	0.58
Education - median (range)
>12 years	47 (15-69)	54 (23-72)	24.5(4-32)	63 (42-110)	63 (36-77)	31 (14-36)
≤12 years	34 (8-57)	54.5 (25-64)	20.5 (6-34)	53 (40-71)	62 (37-74)	28 (19-33)
p	0.10	0.47	0.36	0.05	0.69	0.14
Depression–median (range)
Yes	36 (12-57)	56 (25-64)	23 (4-34)
No	46 (8-69)	46 (8-69)	24 (7-32)
p	0.98	0.83	0.89
Age - r (p)	-0.004(0.98)	-0.11 (0.5)	0.02(0.89)	-0.27(0.03)	-0.11(0.39)	-0.28(0.02)
MS Subtype – median (range)
RRMS (N=31)	49 (8-69)	58 (23-72)	26 (4-34)
SPMS (N=9)	29 (12-39)	42 (25-68)	17 (6-29)
p	<0.001	0.018	0.015
EDSSr(p)	-0.5(<0.001)	-0.46(0.002)	-0.49(0.001)
Disease durationr(p)	-0.23 (0.15)	-0.19 (0.23)	-0.18 (0.27)
Relapse rater(p)	0.04 (0.78)	-0.15 (0.93)	0.18 (0.25)

Mann Whitney U Test; Spearman Correlation