The Impact of Cerebral Amyloid Angiopathy in Various Neurodegenerative Dementia Syndromes: A Neuropathological Study

Table 3

Semiquantitative analysis of the severity of white matter changes (WMCs), lacunar infarcts (LIs), territorial infarcts (TIs), cerebral lobar haematomas (CLHs), cortical microinfarcts (CoMIs), cortical microbleeds (CoMBs) in Alzheimer’s disease (AD), Lewy body disease (LBD), and progressive supranuclear palsy (PSP) according to the grading of the severity of cerebral amyloid angiopathy (CAA).

Items	WMCs	LIs	TIs	LCHs	CoMIs	CoMBs
AD-CAA grading
0:	0.9 (1.0)	0.5 (1.0)	0.2 (0.5)	0.1 (0.3)	0.4 (0.9)	0.9 (0.9)
1-2:	0.9 (0.9 )	0.1 (0.5)	0.1 (0.3)	0.1 (0.3)	0.6 (1.2)	1.1 (0.8)
3:	1.6 (0.8)	0.3 (0.7)	0.4 (0.8)	0.5 (0.7)	2.2 (1.3)	1.8 (07)
LBD-CAA grading
0:	0.8 (1.1)	0.1 (0.3)	0.1 (0.3)	0.2 (0.6)	0.6 (1.1)	0.0 (0.0)
1-2:	0.6 (0.7)	0.1 (0.3)	0.0 (0.0)	0.0 (0.0)	0.4 (1.3)	0.5 (0.4)
3:	0.6 (0.7)	0.1 (0.3)	0.0 (0.0)	0.0 (0.0)	1.2 (0.8)	0.3 (0.2)
PSP-CAA grading
0:	1.0 (1.0)	0.1 (0.2)	0.2 (0.5)	0.1 (0.2)	0.3 (0.6)	1.0 (1.0)
1-2:	1.8 (1.3)	0.8 (1.5)	0.0 (0.0)	0.0 (0.0)	1.0 (1.4)	0.8 (1.5)

p ≤0.05.