Research Article

Minimizing the Diagnostic Delay in Amyotrophic Lateral Sclerosis: The Role of Nonneurologist Practitioners

Table 2

Occurrence of bulbar and spinal signs in our patients.

ā€‰ā€‰At first feeling by the patient (%)At first examination by GP (%)At first examination by the neurologist (%)At diagnosis (%)General prevalence (%)

Bulbar signsSpeech disability32.2233.3347.7861.1192.22
Breathing disability6.671022.2252.2292.22
Swallowing disability13.3313.3337.7851.1186.67
Excessive saliva5.566.6711.112042.22
Tongue fasciculations1.113.3316.6741.1161.11
Tongue atrophy005.5616.6740
PCL1.111.112.227.7818.89

Spinal signsHoffmann sign008.8942.2256.67
LL motor weakness42.2247.7857.787091.11
UL motor weakness31.1135.5652.2272.2293.33
LL fasciculations7.7811.113067.7874.44
UL fasciculations6.678.8936.6765.5671.11
Body fasciculations3.334.4411.1122.2227.78
LL muscle atrophy01.111027.7837.78
UL muscle atrophy6.678.893057.7867.78
LL cramps/pain/spasticity21.1124.4433.3347.7866.67
UL cramps/pain/spasticity12.2218.8927.7842.2266.67
Body cramps/pain/spasticity1.111.112.225.5614.44

LL: lower limbs; PCL: pathological crying and laughing; UL: upper limbs.