Nonadherence to Antiepileptic Medications and Its Determinants among Epileptic Patients at the University of Gondar Referral Hospital, Gondar, Ethiopia, 2019: An Institutional-Based Cross-Sectional Study

Table 4

Bivariable and multivariable analysis of factors associated with nonadherence to antiepileptic medications among epileptic patients at the University of Gondar Referral Hospital, Northwest Ethiopia, 2018 (n = 356).

Independent variables	Category	Nonadherence to AEMs		COR (95% CI)	AOR (95% CI)	value
		No	Yes
Marital status	Single	127	56	1	1	—
	Married	74	44	1.34 (0.82–2.19)	1.80 (0.99–3.24)	0.05
	Divorced and widowed	18	37	4.66 (2.44–8.88)	3.38 (1.54–7.44)	<0.01
Duration of treatment	3 months–1 year	40	13	1	1	—
	1–3 years	63	24	1.17 (0.53–2.56)	1.49 (0.60–3.72)	0.387
	3–5 years	39	29	2.28 (1.03–5.03)	3.58 (1.38–9.29)	0.009
	Above 5 years	77	71	2.83 (1.40–5.73)	3.49 (1.53–7.95)	0.003
Comorbidity	No	206	97	1	1	—
	Yes	13	40	6.53 (3.34–12.77)	2.42 (1.08–5.43)	0.032
Reported side effect	No	200	87	1	1	—
	Yes	19	50	6.05 (3.37–10.86)	3.36 (1.67–6.74)	0.001
Getting health information	No	70	87	3.70 (2.36–5.80)	1.98 (1.11–3.52)	0.019
	Yes	149	50	1	1	—
Perceived stigma	No	174	58	1	1	—
	Yes	45	79	5.26 (3.28–8.43)	2.81 (1.57–5.02)	<0.01
Attitude towards AEMs	Negative	70	95	4.81 (3.03–7.63)	2.46 (1.36–4.45)	0.003
	Positive	149	42	1	1	—