Evaluation of Retinal Structure and Optic Nerve Function Changes in Multiple Sclerosis: Longitudinal Study with 1-Year Follow-Up

Table 1

Demographic and clinical data of multiple sclerosis (MS), healthy controls for OCT (HC OCT), and healthy controls for VEP (HC VEP).

Variable	MS (N = 32)	HC OCT (N = 22)		HC VEP (N = 110)
N (%)
Sex; N (%)
(i) Male	5 (15.6%)	5 (22.7%)	0.72^a	55 (50%)	0.0005^c
(ii) Female	27 (84.4%)	17 (77.3%)		55 (50%)
Median (range)
Age (years)	29.5 (19.0–59.0)	28.5 (20.0–57.0)	0.42^b	29.0 (19.0–55.0)	0.24^b
Disease duration (years)	3.72 (0.50–15.94)	—	—	—
Relapse (n)	4.0 (0.0–13.0)	—	—	—
EDSS	3.0 (0.0–8.0)	—	—	—

EDSS: Expanded Disability Status Scale. ^aFisher’s test. ^bMann–Whitney test. ^cChi-square test.