An Insight into the Current Understanding of Status Epilepticus: From Concept to Management

Table 4

Antiseizure drugs and their mechanism of action.

Sr. no.	Antiseizure drugs	Mechanism
(1)	Carbamazepine, eslicarbazepine acetate, felbamate, lamotrigine, oxcarbazepine, phenytoin, pregabalin, topiramate, valproate, zonisamide	Voltage-gated Na^+ channel blocker
(2)	Gabapentin, pregabalin, ethosuximide, topiramate, valproate, zonisamide, lamotrigine	Voltage-gated Ca^2+ channel blocker
(3)	Barbituates, benzodiazepines, felbamate, topiramate, propofol	GABA receptor antagonist
(4)	Vigabatrine, tiagabine	GABA antagonist
(5)	Perampanel	AMPA antagonist
(6)	Felbamate, ketamine, propofol, magnesium	NMDA receptor antagonist