Obstetrics and Gynecology International
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Acceptance rate8%
Submission to final decision102 days
Acceptance to publication25 days
CiteScore2.100
Impact Factor-

Metastatin as a Marker for Hyperandrogenemia in Iraqi Women with Polycystic Ovary Syndrome

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Obstetrics and Gynecology International publishes articles related to obstetrics, maternal-fetal medicine, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, and sexual medicine.

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Research Article

Serum Leptin as a Marker for Severity of Endometriosis

Background. Endometriosis a disease of theories, and one of the important causes of chronic pelvic pain, dysmenorrhea, dyspareunia, and subfertility. Surgery is the mainstay step for the diagnosis; noninvasive test is the goal in the future. Aim of Study. To test the role of serum leptin in determination of severity of endometriosis. Study Design. A cross-sectional study done in Al-Yarmouk Teaching Hospital from 1st of January 2018 to 1st of January 2019. Methods. 60 BMI-matched patients were involved in the study. A study group of 30 patients were operated either by laparoscopy or laparotomy for many reasons diagnosed as endometriosis by histopathology, and 30 normal women as a control group underwent elective surgery. Blood sample was taken from all patients in the theater room when laparoscopy finding went with endometriosis, and classifying according to surgical staging of endometriosis, the level of serum leptin was measured by ELISA using Human LEP (Leptin) ELISA Kit. The recording of finding of laparoscopy after conforming of diagnosis by histopathology was compared with the result of serum leptin. Result. The result shows no significant difference between the two groups regarding parity and age; however, the level of serum leptin was significantly high in the endometriosis group than in the control group. The value was less than 0.05. Also, the result shows no significant differences between serum leptin in both groups according to the symptom but there was a significant difference with surgical staging. The mean of the level of serum leptin in stage 1 was 214.8, while it was 340.3 in stage 4. Conclusion. Serum leptin can be used as a marker of severity of endometriosis.

Research Article

Use of Cesarean Birth among Robson Groups 2 and 4 at Mizan-Tepi University Hospital, Ethiopia

Background. Primary cesarean birth rates were high among women who were either nulliparous (Group 2) or multiparous (Group 4) with a single, cephalic, term fetus who were induced, augmented, or underwent cesarean birth before labor in our study cohort. Objectives. The objective of this analysis was to determine what risk factors were associated with cesarean birth among Robson Groups 2 and 4. Methods. This study was a prospective hospital-based cross-sectional analysis of a convenience sample of 1,000 women who delivered at Mizan-Tepi University Teaching Hospital in the summer and fall of 2019. Results. Women in Robson Groups 2 and 4 comprised 11.4% (n = 113) of the total population (n = 993). The cesarean birth rate in Robson Group 2 (n = 56) was 37.5% and in Robson Group 4 (n = 57) was 24.6%. In Robson Group 2, of all prelabor cesareans (n = 5), one birth was elective cesarean by maternal request; the intrapartum cesarean births (n = 16) mostly had a maternal or fetal indication (93.8%), with one birth (6.2%) indicated by “failed induction or augmentation,” which was a combined indication. In Robson Group 4, all 4 women delivered by prelabor cesarean had a maternal indication (one was missing data), and 3 of the intrapartum cesareans were indicated by “failed induction or augmentation.” In multivariable modeling of Robson Group 2, having a labor duration of “not applicable” increased the risk of cesarean delivery (RR 2.9, CI (1.5, 5.4)). The odds of requiring maternal antibiotics was the only notable outcome with increased risk (RR 11.1, CI (1.9, 64.9)). In multivariable modeling of Robson Group 4, having a labor longer than 24 hours trended towards a significant association with cesarean (RR 3.6, CI (0.9, 14.3)), and women had a more dilated cervix on admission trended toward having a lower odds of cesarean (RR 0.8, CI (0.6, 1.0)). Conclusion. Though rates of primary cesarean birth among women who have a term, single, cephalic fetus and are induced, augmented, or undergone prelabor cesarean birth are high, those that occur intrapartum seem to be associated with appropriate risk factors and indications, though we cannot say this definitely as we did not perform an audit. More research is needed on the prelabor subgroup as a separate entity.

Research Article

Meta-Analysis of VTE Risk: Ovarian Cancer Patients by Stage, Histology, Cytoreduction, and Ascites at Diagnosis

Venous thromboembolisms (VTEs) have been a leading secondary cause of death among ovarian cancer patients, prompting multiple studies of risk factors. The objective of this meta-analysis is to quantify the associations between VTE and the most commonly reported risk factors among ovarian cancer patients. PubMed, Embase, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) were used to identify observational studies. Two reviewers independently abstracted data and assessed quality via the Newcastle–Ottawa tool. A random effects model was used to calculate the pooled odds ratios for VTE with each of the following exposures: advanced cancer stage, clear cell histology, serous histology, ascites at diagnosis, and complete cytoreduction. The I2 and Q tests were used to evaluate heterogeneity. Twenty cohort studies with 6,324 total ovarian cancer patients, 769 of whom experienced a VTE, were included. The odds of VTE in ovarian cancer patients were higher among patients with cancer stage III/IV (versus cancer stage I/II, pooled odds ratio (OR) 2.73; 95% CI 1.84–4.06; I2= 64%), clear cell (versus nonclear cell) histology (OR 2.11; 95% CI 1.55–2.89; I2 = 6%), and ascites (versus no ascites) at diagnosis (OR 2.12; 95% CI 1.51–2.96; I2 = 32%). Serous (versus nonserous) histology (OR 1.26; 95% CI 0.91–1.75; I2 = 42%) and complete (versus incomplete) cytoreduction (OR 1.05; 95% CI 0.27–4.11; I2 = 88%) were not associated with VTE. This meta-analysis quantifies the significantly elevated odds of VTE in ovarian cancer patients with advanced stage at diagnosis, clear cell histology, and ascites at diagnosis. Further studies are needed to account for confounders and inform clinical decision-making tools.

Research Article

Obstetric Danger Signs: Knowledge, Attitude, Health-Seeking Action, and Associated Factors among Postnatal Mothers in Nekemte Town, Oromia Region, Western Ethiopia—A Community-Based Cross-Sectional Study

Background. Maternal mortality remains unacceptably high due to pregnancy complications and remains the major health problems in many developing countries such as Ethiopia. Having poor knowledge of obstetric danger signs contributes to delays in seeking and receiving skilled care which in turn increases maternal mortality. However, in Ethiopia, studies are lacking regarding the knowledge level of mothers about obstetric danger signs during pregnancy, child birth, and postnatal periods. In Ethiopia, the proportion of those who have full knowledge of these obstetric danger signs during pregnancy, child birth, and postnatal period is not known. Despite few studies are conducted at health facility level focusing on danger signs during pregnancy, the issue of health-seeking action after identifying danger signs and attitude of mothers towards obstetric danger sign was not addressed. Objectives. To determine knowledge, attitude, health-seeking action towards obstetric danger signs, and associated factors among postpartum women. Methods.A community-based cross-sectional study was conducted in Nekemte Town from October 1 to November 30, 2017. Multistage sampling technique was employed to select the total sample size of 621. Ethical clearance was obtained from Wollega University research and ethical committee. A pretested structured questionnaire was used to collect data from respondents. Data were entered to EpiData version 3.1 and exported to SPSS version 20 for analysis. To assess the associations between dependent and independent variables, binary and multivariate logistic regressions were employed, and the strength of association was presented using odds ratios with 95% confidence intervals. Result. Only 197 (32.3%) of respondents were able to spontaneously mention at least five key obstetric danger signs during antepartum, intrapartum, and postpartum (in the three phases) with at least one obstetric danger sign in each phase and thus were considered as having good knowledge of key obstetric danger signs. Government employee (AOR = 3.28, 95% CI: 1.98–5.42), able to read and write (AOR = 4.92, 95% CI: 2.14–11.3), primary school (AOR = 4.90, 95% CI: 2.11–11.4), ANC follow-up (AOR = 6.2, 95% CI: 1.82–21.21), and ANC visit (AOR = 4.07, 95% CI: 2.35–7.06) were significantly associated with knowledge of obstetric danger sign. From 150 (24.6%) participants who faced obstetric danger signs during their last pregnancy, the majority of them, 137 (91.3%), had a good practice which is seeking a health facility for care. Conclusion and Recommendation. Despite their low knowledge level and attitude, the practice of mothers in response to obstetric danger signs was encouraging. Occupation, educational status, ANC follow-up, and number of ANC visits were variables significantly associated with knowledge of obstetric danger signs. Health care providers should provide health education and counseling to increase awareness, and appropriate counseling during antenatal care at each visit is of paramount importance.

Research Article

Smartphone Applications for Period Tracking: Rating and Behavioral Change among Women Users

Background. The use of mobile apps for health and well-being has grown exponentially in the last decade, as such apps were reported to be ideal platforms for behavioral change and symptoms monitoring and management. Objective. This study aimed to systematically review period tracking applications available at Google Play and Apple App Stores and determine the presence, features, and quality of these smartphone apps. In addition, behavioral changes associated with the top 5 rated apps were assessed. Methods. This study used the Systematic Search Criteria through Google Play Store and iTunes Apple Store, using terms related to period tracking. Apps were scanned for matching the inclusion criteria and the included apps were assessed by two reviewers using the Mobile Application Rating Scale (MARS), a tool that was developed for classifying and assessing the quality of mHealth apps. Results. Forty-nine apps met the inclusion criteria. Most of the apps enabled setting user goals, motivations, and interactivity, tracking multiple symptoms or mood changes, allowed notifications, and used graphs to illustrate the tracking result over a specific period of time. The majority of features and functions within these apps were offered for free, while some apps included limited in-app purchases or needed Internet connection to function. Certain apps were reported by participants to promote behavioral change and increase knowledge and awareness regarding monthly periods. Conclusions. Period tracking apps were easy to use and navigate and can hence be readily adopted into routine tracking and management of periods. However, most apps were not based on significant evidence and may need further development to support period-related symptom management.

Research Article

How Menstruation Is Perceived by Adolescent School Girls in Gedeo Zone of Ethiopia?

Introduction. Perception regarding menstruation is insufficiently acknowledged. Lack of adequate perception towards menstruation may make girls vulnerable to mental, emotional, and physical problems. This might also be a reason for the failure of menstrual hygiene practice which in turn can have multiple social and health consequences. Objective. To assess the perception and correlation regarding menstruation among adolescent high school girls in Gedeo zone, Southern Ethiopia. Methods. An institutional-based cross-sectional study was conducted among a randomly selected 791 adolescent high school girls at the Gedeo zone through the multistage sampling technique. Data were collected using an interviewer-administered questionnaire. The data were entered to EPi Info version 3.5 and exported to SPSS version 20.0 for analysis. Frequency tables were used to describe study variables. Odds ratio with 95% confidence interval was computed to determine the level of significance. Result. From a total of 806 adolescent girls that were invited to participate in the study, 791 (98.1%) participated. The mean (±SD) age of respondents was 16.3 (±4.7) years. Living alone in dormitories {OR = 1.75 CI = (1.07, 2.85)}, lower maternal educational status {OR = 4.03, CI = (2.41, 6.74)}, and age of menarche before 12 years {OR = 2.07, CI = (1.02, 4.24)} were factors statistically associated with unfavorable perception regarding menstruation. Conclusion. Most high school girls had an unfavorable perception regarding menstruation. Living alone, lower maternal educational status, and age of menarche before 12 years were factors with statistically significant association with unfavorable perception regarding menstruation. This demonstrates a need to design and implement advocacy programs.

Obstetrics and Gynecology International
 Journal metrics
Acceptance rate8%
Submission to final decision102 days
Acceptance to publication25 days
CiteScore2.100
Impact Factor-
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