The HPV Cellular Transactivator Brn-3a Can Be Used to Predict Cervical Adenocarcinoma and Squamous Carcinoma Precancer Lesions in the Developed and Developing Worlds
Figure 1
The scatter plot ((a) and (b)) and regression line ((c) and (d)) of Brn-3a and E6 mRNA levels in cervical scrapes obtained from women with High-grade Cervical Intraepithelial Neoplasia (HG CIN) (squamous cell carcinoma (SCC) precancer) and High-grade Cervical Glandular Intraepithelial Neoplasia (HG CGIN) (adenocarcinoma (AC) precancer). Note for the scatter plots, the bar designates the mean Brn-3a and E6 mRNA levels for SCC precancer, AC precancer and cervicitis (as a control group).