Obstetrics and Gynecology International

Research Article

The HPV Cellular Transactivator Brn-3a Can Be Used to Predict Cervical Adenocarcinoma and Squamous Carcinoma Precancer Lesions in the Developed and Developing Worlds

Table 2

Presence of Brn-3a and E6 mRNA in the cervix of women in Recife-Brazil with different forms of cervical precancer lesions and a cervicitis control group.
Women from Brazil
PathologyBrn-3a mRNA presentHPV E6 mRNA present
(no. of cases)no. (%)no. (%)
Cervicitis (32 )18 (56.3)15 (46.8)
SCC precancer (32)32 (100)30 (93.7)
AC precancer (17)17 (100)15 (88.2)
SSCC (2)2 (100)2 (100) (%)
Women from England
PathologyBrn-3a mRNA presentHPV E6 mRNA present
(no. of cases)no. (%)no. (%)
Cervicitis (32)15 (46.8)12 (37.5)
SCC precancer (17)16 (94.1)13 (76.4)
AC precancer (4)4 (100)4 (100)
SSCC (0)——
Total no of pathological cases in Study
Total pathological cases inBrn-3a mRNA presentHPV E6 mRNA present
study (no.)no. (%)no. (%)
Cervicitis (64)33 (51.5)27 (42.2)
SCC precancer (49)48 (97.9)33 (67.3)
AC precancer (21)21 (100)19 (90.4)
SSCC (2)2 (100)2 (100)