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Pt no. | Maternal age (years) | Cause of bleeding | Time from start of bleeding to rFVIIa administration (hours:minutes) | No. of rFVIIa doses administered | Measures taken to secure haemostasis before rFVIIa | Measures taken to secure haemostasis after rFVIIa | Blood loss following rFVIIa |
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1 | 33 | Uterine atony | 12:35 | 1 | Uterotonics, curettage, uterine packing | Nil | Stopped |
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2 | 34 | Post emergency Caesarean section | 20:33 | 1 | Aprotinin, ligation of broad ligament bleed point | Bilateral iliac artery ligation, splenectomy | Stopped |
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3 | 30 | Retained placenta, uterine perforation | 2:00 | 1 | TAH (rFVIIa given intraoperatively) | Nil | Stopped |
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4 | 30 | Placental abruption | 9:15 | 1 | Uterotonics | Nil | Stopped |
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5 | 38 | Uterine atony following exit procedure | 1:59 | 1 | Uterotonics | Nil | Decreased |
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6 | 20 | Uterine atony, vaginal lacerations | 2:57 | 1 | Uterotonics, Rusch balloon | Nil | Decreased |
7 | 34 | Intrapartum bleeding with uterine atony following emergency Caesarean section | 5:10 | 3 | Uterotonics, Rusch balloon, TAH (1st dose rFVIIa given intraoperatively) | 2nd rVIIa followed by 4 vessel embolisation, 3rd rFVIIA followed by repair bladder tear and further embolisation | Decreased |
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8 | 46 | Placenta accreta and placenta praevia, | 4:35 | 1 | TAH | Laparotomy but no bleeding point found. | Decreased |
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9 | 32 | Placenta praevia (Jehovah’s Witness) | 8:00 | 1 | Uterotonics, antifibrinolytics, B-Lynch suture | TAH | Decreased |
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10 | 36 | Placental abruption during road traffic accident | 5:00 | 1 | Uterotonics, laparotomy and intra-abdominal packing | Nil | Decreased |
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11 | 38 | Placenta praevia | 3:05 | 1 | Balloon tamponade, vaginal packing | Nil | Decreased |
12 | 36 | Uterine eversion | 1:00 | 1 | Uterotonics, uterine packing, vessel embolisation, TAH (rFVIIa given intraoperatively) | Repeat laparotomy and abdominal packing | Decreased |
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13 | 21 | Placenta praevia | 3:30 | 1 | Uterotonics, antifibrinolytics | TAH | Unchanged |
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14 | 43 | Post elective Caesarean section, broad ligament tear | 4:05 | 1 | Laparotomy and repair of tear | Subtotal hysterectomy | Unchanged |
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15 | 20 | Uterine atony | 3:00 | 1 | Uterotonics, uterine packing, B-Lynch suture, iliac artery ligation, | TAH | Unchanged |
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