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Obstetrics and Gynecology International
Volume 2009 (2009), Article ID 485423, 4 pages
Clinical Study

High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1

1STD Unit, Brazilian Program of STD/Aids, Secretariat for Health Surveillance, Ministry of Health, 70070-600 Brasília, DF, Brazil
2Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 14049-900 Ribeirão Preto, SP, Brazil
3Department of Obstetrics and Gynecology, Medical School of the Federal University of Health Sciences of Porto Alegre, 90020-090 Porto Alegre, RS, Brazil
4Department of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 30150-221 Ribeirão Preto, SP, Brazil

Received 14 May 2009; Accepted 25 July 2009

Academic Editor: Enrique Hernandez

Copyright © 2009 Emilia Moreira Jalil et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To estimate HPV prevalence among pregnant women from Ribeirão Preto, Brazil, and the possible influence of HIV-1 infection on this prevalence. Methods. A cross-sectional study with 44 HIV-positive and 53 HIV-negative pregnant women was conducted. Cervicovaginal specimens were obtained from all women during gynecologic exam. HPV DNA, low and high risk HPV types, was detected using conventional PCR. Statistical analysis used Student's -test, Mann-Whitney test, Fischer's Exact test, and prevalence ratios with 95% confidence interval. Results. HIV-positive pregnant women had higher proportion of HPV infection than HIV-negative pregnant women (79.5% versus 58.5%; ). HPV positivity prevalence ratio for HIV-positive women was 1.36 (95% CI 1.04–1.8; ). There was significant association between HIV viral load levels and HPV positivity ( ). Conclusions. Our results demonstrate higher HPV positivity in HIV-infected pregnant women. Higher values of HIV viral load were associated with HPV positivity.