A Randomized Controlled Trial of Misoprostol and Sulprostone to End Pregnancy after Fetal Death
Table 2
Labor and delivery outcomes.
Outcome*
Misoprostol
Sulprostone
()
()
%
%
Induction-delivery interval (hours)
Median
10.4
12.3
Range
1.7–58.0
2.0 – 74.8
10th–90th centile
4.5–22.0
5.8 – 31.3
Induction-delivery interval
Within 12 hours
41
58.6
34
49.3
Within 24 hours
64
91.4
59
85.5
Within 36 hours
68
97.1
64
92.8
Within 48 hours
69
98.6
67
97.1
Switched to alternative treatment
3
4.3
6
8.7
Use of other uterotonics
19
27.1
16
23.2
Before delivery
6
3
After delivery
13
13
Placental retention hour
14
20.0
11
15.9
Curettage or manual removal of placenta
25
35.7
22
31.9
Placenta delivered spontaneously within 1 hour without curettage or manual removal
At 22 weeks
15/38
39.5
15/3
444.1
At 22–27 weeks
8/10
80.0
9/11
81.8
At 28 weeks
18/21
85.7
18/22
81.8
All women**
42/70
60.0
44/69
63.8
Blood loss (mL)
300 mL
43
61.4
43
62.3
500 mL
15
21.4
14
20.3
1,000 mL
5
7.1
6
8.6
Blood transfusion
1
1.4
3
4.3
*None of the differences between the two groups reaches statistical significance. **Includes 3 women (1 misoprostol and 2 sulprostone) with too uncertain a duration of pregnancy to be classified in the gestational age categories.
