A Randomized Controlled Trial of Misoprostol and Sulprostone to End Pregnancy after Fetal Death

Table 3

Frequency of side effects as recorded by the caregivers.

Outcome*	Misoprostol		Sulprostone
	(𝑛=70)		(𝑛=69)
	𝑛	%	𝑛	%
Nausea and vomiting
None	53	75.7	54	78.3
All nausea/vomiting	5	7.1	8	11.6
Mild, unmedicated	2	2.9	2	2.9
Medicated	3	4.3	6	8.7
Not recorded	12	17.1	7	10.1
Diarrhea
None	61	87.1	62	89.9
All diarrhea	7	10.0	7	10.1
Mild, unmedicated	6	8.6	3	4.3
Medicated	1	1.4	4	5.8
Not recorded	2	2.9	0	0
Use of analgesia
None	12	17.1	10	14.5
Any pain relief	57	81.4	59	85.5
Mild analgesics	11	15.7	10	14.5
Opiates	14	20.0	12	17.4
Epidural	29	41.4	33	47.8
Opiates and epidural	3	4.3	4	5.8
Not recorded	1	1.4	0	0
Hyperthermia (≥38.0°C)*	17	24.3	8	11.6

*None of the differences are statistically significant except for the frequency of hyperthermia (Chi square test: 𝑃<.05).