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Obstetrics and Gynecology International
Volume 2009, Article ID 564567, 3 pages
Case Report

Intra-Abdominal Bleeding during Pregnancy, Preterm Delivery, and Placental Polyp in a Long-Term Survivor of Neuroblastoma: A Case Report

Department of Perinatology, National Center of Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan

Received 20 May 2009; Revised 16 August 2009; Accepted 24 September 2009

Academic Editor: Julian T. Parer

Copyright © 2009 Noriyoshi Watanabe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. There are few reports of pregnancies in long-term survivors of pelvic neuroblastoma. Case. A 30-year-old Japanese woman with a history of pelvic neuroblastoma in her childhood, which was treated with surgical resection, chemotherapy, and radiation. Her pregnancy continued with conservative management, but she delivered a 510 g female infant at 23 weeks of gestation due to sudden onset of labor pain. She also had a placental polyp and developed massive postpartum bleeding. Conclusion. Cancer treatment, especially radiation therapy, in childhood may cause adverse outcomes during pregnancy in long-term survivors of neuroblastoma.