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Obstetrics and Gynecology International
Volume 2009 (2009), Article ID 726593, 6 pages
http://dx.doi.org/10.1155/2009/726593
Research Article

Functional Role of P-Glycoprotein and Binding Protein Effect on the Placental Transfer of Lopinavir/Ritonavir in the Ex Vivo Human Perfusion Model

1Department of Obstetrics and Gynecology, Louis Mourier Hospital, AP-HP, Paris 7 University, 92701 Colombes, France
2Faculty of Pharmacy, University Paris-Sud, EA2706, 92296 Châtenay-Malabry, France
3Department of Pediatric Pharmacology, Saint Vincent de Paul Hospital, AP-HP, Paris 5 University, 75014 Paris, France
4Department of Pharmacy, Pitié-Salpétrière Hospital, AP-HP, 75013 Paris, France

Received 17 September 2008; Accepted 2 February 2009

Academic Editor: Michael G. Ross

Copyright © 2009 Pierre-Francois Ceccaldi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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