Expression of Semaphorin 3F and Its Receptors in Epithelial Ovarian Cancer, Fallopian Tubes, and Secondary Müllerian Tissues

Table 1

Epithelial expression of S3F and NP-2 decreases while NP-1 increases with ovarian epithelial tumor progression.

	S3F	NP-2	NP-1
N	67.5±1.6	71.4±3.0	80.5±1.4
Cy	42.9±2.3	48.8±2.1	86.5±1.8
	* 𝑃≤.001⋄𝑃≤.05	* 𝑃≤.001⋄𝑃≤.001	* 𝑃≤.001⋄𝑃≤.001
WD	21.6±3.9	19.2±4.4	100
	^**𝑃≤.001∘𝑃≤.05	^**𝑃≤.001∘𝑃≤.001	^**𝑃≤.001∘𝑃≤.001
PD	29.5±1.5	17.1±2.3	100
	^**𝑃≤.001∘𝑃≤.05	^**𝑃≤.001∘𝑃≤.001	^**𝑃≤.001∘𝑃≤.001
IC	100	100	100
PC	100	85.7±4.5	82.5±2
FT	100	72.2±3.6	100

*N versus Cy ^**N versus WD+PD ⋄N + FT versus Cy ∘N + FT versus WD+PD. Abbreviations: normal (N), serous cystadenoma (Cy), well-differentiated serous adenocarcinoma (WD), poorly differentiated serous adenocarcinoma (PD), inclusion cyst (IC), paraovarian cyst (PC), and fallopian tube (FT). Data represent the average percent of positive epithelium expressing S3F, NP-2, and NP-1 ± SEM.