Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKB𝜶/AKT and Induces Apoptosis

Figure 2

Immunoblot for PKBα/AKT, cleaved PARP, and EGFR. HTR-8/SV neo cell treatments are as follows: Lane (1) serum-starved control, (2) with EGF (30 ng/mL, 5 min), (3) Iressa (1 μM, 20 h), and (4) EGF (30 ng/mL, 5 min) + Iressa (1 μM, 20 h).