Review Article

Oocyte Cryostorage to Preserve Fertility in Oncological Patients

Table 1

Results from different oocyte cryopreservation protocols: slow freezing (high-sucrose concentration) and vitrification.

Vitrification (VIT)Slow freezing (SF)SurvivalFertilizationPregnancyMiscarriageEgg donation program

Chen et al., 2005 [44]Yes75% (119)67% (80)33% (7)0%Partially
Li et al., 2005 [45]Yes90% (73/81)82% (60/73)47% (7/15)28% (2/7)Partially
Kuwayama et al., 2005 [46]Yes91% (58/64)81% (52/64)41% (12/29)17% (2/12)No
Borini et al., 2006 [47]Yes43,4% (306/705)51,6% (158/306)19,2% (14/73)28,6% (4/14)No
Barritt et al., 2007 [48]Yes86,1% (68/79)89,7% (61/68)75% (3/4)NSYes
Lucena et al., 2006 [49]Yes96,7% (143)87,2% (105)56,5% (13)NSYes
Antinori et al., 2007 [50]Yes99,4% (328/330)92,9% (305/328)32,5% (39/120)20,5% (8/39)No
Cobo et al., 2008 [51]Yes96,9% (224/231)76,3% (171/224)65,2% (15/23)20% (3/15)Yes
Parmegiani et al., 2008 [52]Yes75,1% (328/437)80% (227/328)19% (16/83)31,2% (5/16)No
Cao et al., 2009 [42] Yes YesSF 61% (75/123)SF 61,3% (46/75)NDNDNo
VIT 91,8% (268/292)VIT 67,9% (182/268)NDNDNo
Smith et al., 2010 [53] Yes YesSF 65% (155/238)SF 67% (104/155)SF 13% (4/30)SF 25% (1/4)No
VIT 75% (260/349)VIT 77% (200/260)VIT 38% (18/48)VIT 18% (4/18)No
Rienzi et al., 2010 [54]Yes97% (120/124)79,2% (95/120)30,8% (15/39)20% (3/15)No
Cobo et al., 2010 [55]Yes92,5% (3039)73,3% (NS)55,4% (148)NSYes

NS = Data not reported.
ND = Data not calculated, not a study endpoint.