Review Article

Intrauterine Adhesions following Conservative Treatment of Uterine Fibroids

Table 1

Intrauterine synechiae following resectoscopic myomectomy. Second-look hysteroscopy.

AuthorInstrumentSecond-look intervalFibroidsAdditional treatmentAdhesions/second-look hysteroscopiesAdhesion rate

Taskin et al. 2000 [9]monopolar14–30 days singleno/placebo8/2236.36%
Danazol7/2035%
multipleno/placebo6/1346.15%
Danazol6/1442.85%

Guida et al. 2004 [11]bipolar3 months single*no/placebo8/2433.33%
a–c hyaluronic acid gel4/2516%

Yang et al. 2008 [10] monopolar* 1–3 monthssingleNo2/1321.5%
2, nonapposingIUD, 1 month0/50%
≥2 apposingIUD, 1 month7/978%
≥2 apposingearly lysis 1-2 weeks0/70%

Touboul et al. 2009 [13]bipolar2 monthssingle*No4/537.5%

Roy et al. 2010 [14]monopolar6 weekssingleestradiol valerate (6 weeks) antibiotics (5 days)2/1861.07%

Total54/51010.58%

*Extrapolated, but not clearly stated on the original paper.