Obstetrics and Gynecology International / 2012 / Article / Tab 2

Review Article

Multiple Approaches for Individualized Fertility Protective Therapy in Cancer Patients

Table 2

Rate of chemotherapy-induced amenorrhea, according to regimen and age.

RegimenAge <30 yrsAge 30–40 yrsAge >40 yrs

No treatment1%< 5%20–25%
Ac x413%60%
CMF x619%35%85%
CAF/CEF x630%85%
AC x4->Dtax55%

AC: doxorubicin/cyclophosphamide,
CMF: cyclophosphamide/methotrexate/5-fluorouracil,
CAF: cyclophosphamide/doxorubicin/5-fluorouracil,
CEF: cyclophosphamide/epirubicin/5-fluorouracil,
Dtax: docetaxel.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.