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Study | Inclusion criteria | Exclusion criteria | | Gestational age at testing (wk) | CL at inclusion | CL cutoff (mm) | Outcome | Design | Representative spectrum of patients | Adequate description of test procedure | Practitioner blinded to measurement results | Reporting on study withdrawals |
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Fuchs | Twins, regular and painful uterine contractions | Cervical cerclage, ruptured membranes, and dilatation >3 cm | 87 | 24–36 | 20 mm (1–45) Median (IQR) | 25 | Delivery within 7 days | Prospective cohort | Yes | Yes | No | Yes |
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Crane | Twins, regular uterine contraction with cervical dilatation, effacement, and/or change in consistency | Cervical cerclage, placenta previa, ruptured membranes, vaginal bleeding, dilatation >3 cm, and stillbirth | 26 | 23–33 | 25 mm (14.0) Mean (SD) | 30 | Preterm birth <34 and <37 weeks | Prospective cohort | Yes | Yes | No | No |
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Gonzalez | Twins, regular uterine contraction with cervical changes (effacement of at least 50% or dilatation of at least 1 finger) | Cervical cerclage, maternal or fetal contraindication to continue pregnancy | 66 | <34 | Not reported | 20, 30 | Preterm birth <34 and <37 weeks | Prospective cohort | Yes | Yes | No | No |
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Venditelli | Twins, regular uterine contraction, and/or cervical effacement or dilatation | Cerclage, fetal anomalies, placenta previa, ruptured membranes, vaginal blood loss, dilatation >3 cm, stillbirth, and delivery <24 weeks after admission | 26 | 18–36 | Not reported | 30 | Preterm birth <37 weeks | Prospective cohort | Yes | Yes | Yes | Yes |
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Yoshizato | Twins, regular uterine contraction with cervical dilatation, effacement, and/or change in consistency | TTTS, uterine anomalies, conization, vaginal blood loss, PE, hypertension, diabetes, and history of PTB | 21 | 16–35 | 22 mm (5.5) Mean (SD) | 25 | Preterm birth <34 and <37 weeks | Prospective cohort | Yes | Yes | No | No |
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