An Elevated Maternal Plasma Soluble fms-Like Tyrosine Kinase-1 to Placental Growth Factor Ratio at Midtrimester Is a Useful Predictor for Preeclampsia

Table 4

Area under the curve from the receiver operating characteristic curve analysis of sFlt-1, PlGF, and sFlt-1/PlGF ratio.

Variable	AUC	95% confidence interval	Sensitivity (%) at FPR
			5%	10%	15%
sFlt-1	0.875	0.823–0.926	44.6	73.5	83.6
PlGF	0.855	0.81–0.90	14.7	64	74.7
sFlt-1/PlGF ratio	0.917	0.88–0.954	59	81.9	91.6

AUC: area under the curve; FPR: false positive rate; sFlt-1: soluble fms-like tyrosine kinase 1; PlGF: placental growth factor.
False positive rate was calculated as 100 − specificity.