Trimethoprim Use prior to Pregnancy and the Risk of Congenital Malformation: A Register-Based Nationwide Cohort Study

Figure 1

Incidence of types of major congenital malformation in children of women exposed to trimethoprim before conception as compared to children of women unexposed to trimethoprim before conception. Only types of malformations reduced by folic acid supplementation before or during pregnancy are included in the figure. Odds ratio (95% CI).