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Obstetrics and Gynecology International
Volume 2013, Article ID 479541, 5 pages
http://dx.doi.org/10.1155/2013/479541
Review Article

The Estrogen Receptor Joins Other Cancer Biomarkers as a Predictor of Outcome

Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA

Received 17 June 2013; Accepted 10 September 2013

Academic Editor: Eric Prossnitz

Copyright © 2013 Kimberly K. Leslie et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Endometrial cancer, the most common gynecologic malignancy in the United States, is on the rise, and survival is worse today than 40 years ago. In order to improve the outcomes, better biomarkers that direct the choice of therapy are urgently needed. In this review, we explore the estrogen receptor as the most studied biomarker and the best predictor for response for endometrial cancer reported to date.