The Natural History of Uterine Leiomyomas: Light and Electron Microscopic Studies of Fibroid Phases, Interstitial Ischemia, Inanosis, and Reclamation
Figure 9
Cytoplasmic and nuclear atrophy. The eosinophilic cytoplasm of the fibroid myocytes in (b) is indistinct but appears diminished and less abundant than that of the myometrial myocytes in (a), and there is an obvious increase in the stroma that is separating the fibroid cells of this Phase 4 tumor. In addition, the nuclei of the myometrial cells in (a) are uniformly long and straight (arrow), while the fibroid nuclei in (b) exhibit variation in length and contour (arrows) and often appear to be shortened, suggestive of early nuclear shrinkage. Original objective magnification of both (a) and (b): 40x.
