Contemporary Clinical Management of Endometrial Cancer

Table 2

Type I and II endometrial cancers.

	Type I endometrial cancers	Type II endometrial cancers
Hormonal impact	Estrogen dependent	Estrogen independent
Histology	Endometrioid adenocarcinomas	Clear-cell, serous, uterine carcinosarcomas
Patient population	Younger, obese, perimenopausal	Older, thin, postmenopausal
Distribution	85%	15%
Prognosis	Better differentiated	More aggressive, proportionally higher mortality
Genetic mutations	Kras, PTEN, MLH1	p53, erbB2