Review Article
Contemporary Clinical Management of Endometrial Cancer
Table 7
NCCN guidelines for adjuvant treatment of early-stage endometrial cancer.
| Stage | Adverse risk factors | | Grade | | | | |
| IA | Not present | Observe | Observe or brachytherapy | Observe or brachytherapy | Present | Observe or brachytherapy | Observe or brachytherapy
± WPRT (category 2B) | Observe or brachytherapy
WPRT | IB | Not present | Observe or brachytherapy | Observe or brachytherapy | Observe or brachytherapy
WPRT | Present | Observe or brachytherapy
WPRT | Observe or brachytherapy
WPRT | WPRT brachytherapy chemotherapy (category 2B) or observe (category 2B) |
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Risk factors: age >60; lymphovascular space invasion (LVSI); Tumor size >2 cm; lower uterine (cervical/glandular) involvement. WPRT: whole pelvic radiation therapy.
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