Contemporary Clinical Management of Endometrial Cancer

Table 9

Adjuvant treatment in endometrial cancer trials: radiation versus chemotherapy versus combination.

Study	𝑁	Stage	Drug regimen	5-year PFS (%)	5-year OS (%)
Randall; GOG 122	386	III/IV	AP versus WAI	50; 38	55; 42
Maggi	340	I-III	CAP versus PRT	63; 63	66; 60
Susumu; JGOG	385	I-III	CAP versus PRT	82; 84	85; 87
Hogberg	372	I-III	Various versus PRT	79; 72	88; 78
Homesely; GOG 184	552	III/IV	PRT + AP; PRT + TAP	62 (3 year); 63 (3 year)	NS

AP: doxorubicin-cisplatin;
WAI: Whole-abdominal irradiation;
CAP: cyclophosphamide-doxorubicin-cisplatin;
PRT: Pelvic radiation therapy;
TAP: paclitaxel-doxorubicin-cisplatin.