Gene Expression of Leptin and Long Leptin Receptor Isoform in Endometriosis: A Case-Control Study

Figure 1

Leptin and long leptin receptor isoform (OB-R_L) gene expression in endometriosis. (a) Ectopic endometrium and eutopic endometrium of patients with endometriosis. Values are expressed as n-fold difference in relation to the calibrator sample (ΔΔCt method). ^∗∗𝑃<0.001 (leptin mRNA ectopic versus eutopic endometrium); ^∗𝑃<0.05 (OB-R_L mRNA ectopic versus eutopic endometrium) (Wilcoxon signed-rank test). (b) Leptin gene expression and (c) long leptin receptor isoform (OB-R_L) in eutopic endometrium of non-endometriosis controls and ectopic endometrium of minimal/mild and moderate/severe endometriosis. Values are expressed as n-fold difference in relation to the calibrator sample (ΔΔCt method). Asterisks indicate significant difference in comparison to controls. ^∗𝑃<0.05; ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001   (Mann-Whitney U).

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