Review Article
Early Prediction of Preeclampsia
Table 1
Estimated detection rates of preeclampsia (PE) requiring delivery before 34, 37, and 42 weeks’ gestation, at false positive rates (FPR) of 5% and 10%.
| Screening test | FPR (%) | Detection rate (%) | PE < 34 weeks | PE < 37 weeks | PE < 42 weeks |
| Maternal characteristics | 5.0 | 36 | 33 | 29 | 10.0 | 51 | 43 | 40 | Uterine artery pulsatility index (Ut-PI) | 5.0 | 59 | 40 | 31 | 10.0 | 75 | 55 | 42 | Mean arterial pressure (MAP) | 5.0 | 58 | 44 | 37 | 10.0 | 73 | 59 | 54 | Pregnancy associated plasma protein-A (PAPP-A) | 5.0 | 44 | 37 | 32 | 10.0 | 55 | 48 | 42 | Placental growth factor (PlGF) | 5.0 | 59 | 41 | 29 | 10.0 | 72 | 54 | 40 | MAP and Ut-PI | 5.0 | 80 | 55 | 35 | 10.0 | 90 | 72 | 57 | PAPP-A and PlGF | 5.0 | 60 | 43 | 30 | 10.0 | 74 | 56 | 41 | Ut-PI, MAP, and PAPP-A | 5.0 | 82 | 53 | 36 | 10.0 | 93 | 75 | 60 | Ut-PI, MAP, and PlGF | 5.0 | 87 | 61 | 38 | 10.0 | 96 | 77 | 53 | Ut-PI, MAP, PAPP-A, and PlGF | 5.0 | 93 | 61 | 38 | 10.0 | 96 | 77 | 54 |
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