Current Status of Comprehensive Chromosome Screening for Elective Single-Embryo Transfer

Table 1

Comparison of available CCS for 24 chromosomes.

	aCGH	dPCR	SNP array	Real-time qPCR	NGS
Test time (hours)	12–24	8	16–72	4	15
Single gene disease	Y^#	Y*	Y*	Y*	Y
Resolution	Medium	Low	High	Low	High
WGA needed	Y	N	Y	N	Y
Probe number	2~32 K	~20	262~370 K	96	3 × 10^9
Posttest algorithm	Moderate	Easy	Moderate	Easy	Intensive
Cost ($)	High	Medium	High	Low	Very high

#Only deletion/duplication can be detected; *with known mutations.