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Obstetrics and Gynecology International
Volume 2014, Article ID 601932, 9 pages
http://dx.doi.org/10.1155/2014/601932
Research Article

Chlamydia trachomatis Antibody Testing in Vaginal Mucosal Material versus Blood Samples of Women Attending a Fertility Clinic and an STI Clinic

1Epidemiology & Surveillance Unit, Centre for Infectious Disease Control, National Institute of Public Health and the Environment (RIVM), P.O. Box 1 (75), 3720 BA Bilthoven, The Netherlands
2Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands
3STI AIDS Netherlands (SOA AIDS Nederland), P.O. Box 10845, 1001 EV Amsterdam, The Netherlands
4Department of General Practice, AMC-UVA, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands
5Laboratory of Immunogenetics, Department of Medical Microbiology and Infection Control, VU University Medical Centre, De Boelelaan 1105, 1081 HV Amsterdam, The Netherlands
6Institute of Public Health Genomics, Department of Genetics and Cell Biology, Research Institutes CAPHRI and GROW, Faculty of Health, Medicine & Life Sciences, University of Maastricht, P.O. Box 616, 6200 MD Maastricht, The Netherlands
7Julius Centre UMCU, P.O. Box 85500, 3508 GA Utrecht, The Netherlands

Received 15 November 2013; Revised 23 January 2014; Accepted 6 February 2014; Published 13 March 2014

Academic Editor: Deborah A. Wing

Copyright © 2014 Ingrid V. F. van den Broek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. Westrom, R. Joesoef, G. Reynolds, A. Hagdu, and S. E. Thompson, “Pelvic inflammatory disease and fertility: a cohort study of 1,844 women with laparoscopically verified disease and 657 control women with normal laparoscopic results,” Sexually Transmitted Diseases, vol. 19, no. 4, pp. 185–192, 1992. View at Google Scholar · View at Scopus
  2. C. L. Haggerty, S. L. Gottlieb, B. D. Taylor, N. Low, F. Xu, and R. B. Ness, “Risk of sequelae after chlamydia trachomatis genital infection in women,” Journal of Infectious Diseases, vol. 201, supplement 2, pp. S134–S155, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. C. E. French, G. Hughes, A. Nicholson et al., “Estimation of the rate of pelvic inflammatory disease diagnoses: trends in England, 2000–2008,” Sexually Transmitted Diseases, vol. 38, no. 3, pp. 158–162, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Bonneau, O. Chanelles, C. Sifer, and C. Poncelet, “Use of laparoscopy in unexplained infertility,” European Journal of Obstetrics Gynecology and Reproductive Biology, vol. 163, pp. 57–61, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. W. Eggert-Kruse, G. Rohr, T. Demirakca et al., “Chlamydial serology in 1303 asymptomatic subfertile couples,” Human Reproduction, vol. 12, no. 7, pp. 1464–1475, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. J. E. den Hartog, J. A. Land, F. R. M. Stassen, A. G. H. Kessels, and C. A. Bruggeman, “Serological markers of persistent C. trachomatis infections in women with tubal factor subfertility,” Human Reproduction, vol. 20, no. 4, pp. 986–990, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. G. S. Wills, P. J. Horner, R. Reynolds et al., “Pgp3 antibody enzyme-linked immunosorbent assay, a sensitive and specific assay for seroepidemiological analysis of Chlamydia trachomatis infection,” Clinical and Vaccine Immunology, vol. 16, no. 6, pp. 835–843, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. N. M. Budrys, S. Gong, A. K. Rodgers et al., “Chlamydia trachomatis antigens recognized in women with tubal factor infertility, normal fertility, and acute infection,” Obstetrics and Gynecology, vol. 119, no. 5, pp. 1009–1016, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. S. F. Coppus, J. A. Land, B. C. Opmeer et al., “Chlamydia trachomatis IgG seropositivity is associated with lower natural conception rates in ovulatory subfertile women without visible tubal pathology,” Human Reproduction, vol. 26, no. 11, pp. 3061–3067, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. D. E. Moore, L. R. Spadoni, and H. M. Foy, “Increased frequency of serum antibodies to Chlamydia trachomatis in infertility due to distal tubal disease,” The Lancet, vol. 2, no. 8298, pp. 574–577, 1982. View at Google Scholar · View at Scopus
  11. R. B. Jones, B. R. Ardery, S. L. Hui, and R. E. Cleary, “Correlation between serum and antichlamydial antibodies and tubal factor as a cause of infertility,” Fertility and Sterility, vol. 38, no. 5, pp. 553–558, 1982. View at Google Scholar · View at Scopus
  12. J. W. Mouton, M. F. Peeters, J. H. van Rijssort-Vos, and R. P. Verkooyen, “Tubal factor pathology caused by Chlamydia trachomatis: The role of serology,” International Journal of STD and AIDS, vol. 13, supplement 2, pp. 26–29, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. E. Lyytikäinen, M. Kaasila, E. Hiltunen-Back et al., “A discrepancy of Chlamydia trachomatis incidence and prevalence trends in Finland 1983–2003,” BMC Infectious Diseases, vol. 8, article 169, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. F. van Aar, M. de Moraes, S. A. Morré et al., “Chlamydia trachomatis IgG seroprevalence in the general population of the Netherlands in 1996 and in 2007: differential changes by gender and age,” Sexually Transmitted Infections, 2014. View at Publisher · View at Google Scholar
  15. C. M. Lardenoije and J. A. Land, “Chlamydia antibody testing for tubal factor subfertility,” Nederlands Tijdschrift voor Geneeskunde, vol. 151, no. 36, pp. 1981–1985, 2007 (Dutch). View at Google Scholar · View at Scopus
  16. J. E. den Hartog, C. M. J. G. Lardenoije, J. L. Severens, J. A. Land, J. L. H. Evers, and A. G. H. Kessels, “Screening strategies for tubal factor subfertility,” Human Reproduction, vol. 23, no. 8, pp. 1840–1848, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. S. L. Gottlieb, S. M. Berman, and N. Low, “Screening and treatment to prevent sequelae in women with Chlamydia trachomatis genital infection: how much do we know?” Journal of Infectious Diseases, vol. 201, supplement 2, pp. S156–S167, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. R. C. Brunham, C. C. Kuo, L. Cles, and K. K. Holmes, “Correlation of host immune response with quantitative recovery of Chlamydia trachomatis from the human endocervix,” Infection and Immunity, vol. 39, no. 3, pp. 1491–1494, 1983. View at Google Scholar · View at Scopus
  19. T. Agrawal, V. Vats, S. Salhan, and A. Mittal, “Mucosal and peripheral immune responses to chlamydial heat shock proteins in women infected with Chlamydia trachomatis,” Clinical and Experimental Immunology, vol. 148, no. 3, pp. 461–468, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. E. M. van der Snoek, J. M. Ossewaarde, W. I. van der Meijden, P. G. H. Mulder, and H. B. Thio, “The use of serological titres of IgA and IgG in (early) discrimination between rectal infection with non-lymphogranuloma venereum and lymphogranuloma venereum serovars of Chlamydia trochomotis,” Sexually Transmitted Infections, vol. 83, no. 4, pp. 330–334, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. H. J. de Vries, V. Smelov, S. Ouburg et al., “Anal lymphogranuloma venereum infection screening with IgA anti-chlamydia trachomatis-specific major outer membrane protein serology,” Sexually Transmitted Diseases, vol. 37, no. 12, pp. 789–795, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. J. A. Land, A. P. Gijsen, A. G. H. Kessels, M. E. P. Slobbe, and C. A. Bruggeman, “Performance of five serological chlamydia antibody tests in subfertile women,” Human Reproduction, vol. 18, no. 12, pp. 2621–2627, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. S. A. Morré, C. Munk, K. Persson et al., “Comparison of three commercially available peptide-based immunoglobulin G (IgG) and IgA assays to microimmunofluorescence assay for detection of Chlamydia trachomatis antibodies,” Journal of Clinical Microbiology, vol. 40, no. 2, pp. 584–587, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. S. C. M. Trienekens, F. D. H. Koedijk, I. V. F. van den Broek et al., “Sexually transmitted infections, including HIV, in the Netherlands in 2011,” RIVM Rapport 201051001, National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands, 2012. View at Google Scholar
  25. R. E. Johnson and S. Berman Sexual, “Transmission: Chlamydia trachomatis,” in Modern Infectious Disease Epidemiology: Concepts, Methods, Mathematical Models and Public HealthVerlag, A. Krämer, M. Kretzschmar, and K. Krickeberg, Eds., pp. 359–382, Springer, New York, NY, USA.
  26. S. A. Morré, A. J. C. van den Brule, L. Rozendaal et al., “The natural course of asymptomatic Chlamydia trachomatis infections: 45% clearance and no development of clinical PID after one-year follow-up,” International Journal of STD and AIDS, vol. 13, supplement 2, pp. 12–18, 2002. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Molano, C. J. Meijer, E. Weiderpass et al., “The natural course of Chlamydia trachomatis infection in asymptomatic Colombian women: a 5-year follow-up study,” Journal of Infectious Diseases, vol. 191, no. 6, pp. 907–916, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Askienazy-Elbhar and J. Henry-Suchet, “Persistent “silent” Chlamydia trachomatis female genital tract infections,” Infectious Diseases in Obstetrics and Gynecology, vol. 7, no. 1-2, pp. 31–34, 1999. View at Google Scholar · View at Scopus
  29. J. A. Land, A. P. Gijsen, J. L. H. Evers, and C. A. Bruggeman, “Chlamydia trachomatis in subfertile women undergoing uterine instrumentation: screen or treat?” Human Reproduction, vol. 17, no. 3, pp. 525–527, 2002. View at Google Scholar · View at Scopus
  30. J. E. den Hartog, S. A. Morré, and J. A. Land, “Chlamydia trachomatis-associated tubal factor subfertility: immunogenetic aspects and serological screening,” Human Reproduction Update, vol. 12, no. 6, pp. 719–730, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. T. Agrawal, V. Vats, S. Salhan, and A. Mittal, “The mucosal immune response to Chlamydia trachomatis infection of the reproductive tract in women,” Journal of Reproductive Immunology, vol. 83, no. 1-2, pp. 173–178, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. W. M. Geisler, S. G. Morrison, M. L. Doemland et al., “Immunoglobulin-specific responses to Chlamydia elementary bodies in individuals with and at risk for genital chlamydial infection,” The Journal of Infectious Diseases, vol. 206, pp. 1836–1843, 2012. View at Google Scholar
  33. S. J. Usala, F. O. Usala, R. Haciski, J. A. Holt, and G. F. B. Schumacher, “IgG and IgA content of vaginal fluid during the menstrual cycle,” Journal of Reproductive Medicine for the Obstetrician and Gynecologist, vol. 34, no. 4, pp. 292–294, 1989. View at Google Scholar · View at Scopus
  34. M. Safaeian, R. T. Falk, A. C. Rodriguez et al., “Factors associated with fluctuations in IgA and IgG levels at the cervix during the menstrual cycle,” Journal of Infectious Diseases, vol. 199, no. 3, pp. 455–463, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. R. P. Verkooyen, M. F. Peeters, J. H. van Rijsoort-Vos, W. I. van der Meijden, and J. W. Mouton, “Sensitivity and specificity of three new commercially available Chlamydia trachomatis tests,” International Journal of STD and AIDS, vol. 13, supplement 2, pp. 23–25, 2002. View at Publisher · View at Google Scholar · View at Scopus