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Obstetrics and Gynecology International
Volume 2016, Article ID 2968410, 5 pages
Research Article

Histopathological and Digital Morphometrical Evaluation of Uterine Leiomyoma in Brazilian Women

1Programa de Pós-Graduação em Patologia, Universidade Federal de Pernambuco (UFPE), Campus Universitário, Avenida Morais Rego s/n, Cidade Universitária, 50670-910 Recife, PE, Brazil
2Laboratório de Imunopatologia Keizo Asami (LIKA), UFPE, Recife, PE, Brazil
3Centro Acadêmico de Vitória, UFPE, Vitória de Santo Antão, PE, Brazil
4Departamento de Patologia, UFPE, Recife, PE, Brazil

Received 1 October 2015; Revised 14 February 2016; Accepted 13 March 2016

Academic Editor: W. T. Creasman

Copyright © 2016 Ana Paula Fernandes da Silva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The current study aims to evaluate histopathological and digital morphometrical aspects associated with uterine leiomyomas in one hundred and fifty (150) patients diagnosed with leiomyoma. Uterine tissues were subjected to the histopathological and digital morphometric analyses of the interstitial collagen distribution. The analysis of medical records indicates that most of the women diagnosed with uterine leiomyomas (68.7%) are between 37 and 48 years old. As for the anatomic location of the tumors, approximately 61.4% of the patients had intramural and subserosal lesions. In 50% of the studied cases, the patients developed uterine leiomyomatosis (with more than eight tumors). As for the morphometric study, the average size of the interstitial collagen distribution held approximately 28.53% of the capture area, whereas it was of 7.43% in the normal tissue adjacent to the tumor. Another important aspect observed in the current study was the high rate of young women subjected to total hysterectomy, a fact that resulted in early and definitive sterility.