White Matter Damage in 4,725 Term-Born Infants Is Determined by Head Circumference at Birth: The Missing Link

Table 1

Various forms of white matter damage (WMD) in term-born neonates at 37–43 weeks gestation diagnosed by cranial ultrasound examination at a median of 8 days (range 1–30 days) after birth.

#	Patient code	Lateral ventricle asymmetry	Lateral ventricle enlargement	Lateral ventricle bilateral enlargement	Posthemorrhagic hydrocephalus	Diffuse periventricular leukomalacia	Cystic periventricular leukomalacia (porencephaly)	White matter damage present
1	28	1	1	0	0	0	0	1
2	34	1	0	0	1	0	0	1
3	71	1	1	0	0	0	0	1
4	89	0	1	1	0	0	0	1
5	106	1	1	0	0	0	0	1
6	118	0	1	1	0	0	0	1
7	146	1	1	0	0	0	0	1
8	150	1	1	0	0	0	0	1
9	198	0	1	1	0	0	0	1
10	228	1	1	0	0	0	0	1
11	239	1	1	0	0	0	0	1
12	244	1	1	0	0	0	0	1
13	250	1	1	0	0	0	0	1
14	273	0	1	1	0	0	0	1
15	281	0	1	1	0	0	0	1
16	282	0	1	1	0	0	0	1
17	286	1	1	0	1	0	0	1
18	295	0	0	0	1	0	0	1
19	295	1	1	0	0	0	0	1
20	321	0	1	1	0	0	0	1
21	328	1	1	0	0	0	0	1
22	332	1	1	0	0	0	0	1
23	337	1	1	0	0	0	0	1
24	353	1	1	0	0	0	0	1
25	370	0	1	1	0	0	0	1
26	371	0	1	1	0	0	0	1
27	373	0	1	1	0	0	0	1
28	393	0	1	1	0	0	0	1
29	394	0	1	1	0	0	0	1
30	395	1	1	0	0	0	0	1
31	406	1	1	0	0	0	0	1
32	441	0	1	1	0	0	0	1
33	445	0	1	1	0	0	0	1
34	492	0	1	1	0	0	0	1
35	505	0	1	1	0	0	0	1
36	517	0	1	1	0	0	0	1
37	546	0	1	1	0	0	0	1
38	548	0	1	1	0	0	0	1
39	562	0	1	1	0	0	0	1
40	572	1	1	0	0	0	0	1
41	582	0	1	1	0	0	0	1
42	600	0	1	1	0	0	0	1
43	627	1	1	0	0	0	0	1
44	630	1	1	0	0	0	0	1
45	634	0	0	0	0	1	0	1
46	684	0	1	1	0	0	0	1
47	697	0	1	1	0	0	0	1
48	769	1	1	0	0	0	0	1
49	813	1	1	0	0	0	0	1
50	850	1	1	0	0	0	0	1
51	876	1	1	0	0	0	0	1
52	892	0	1	1	0	0	0	1
53	899	0	0	0	0	1	0	1
54	902	0	1	1	0	0	0	1
55	915	1	1	0	0	0	0	1
56	962	0	1	1	0	0	0	1
57	962	1	1	0	0	0	0	1
58	1,093	1	1	0	0	0	0	1
59	1,118	0	1	1	0	0	0	1
60	1,148	1	1	0	0	0	0	1
61	1,445	0	1	1	0	0	0	1
1–61	Sum	29/61	57/61	29/61	3/61	2/61	0/61	61/61
	%	48	93	48	5	3	0	100

1 = yes; 0 = no; Bilateral enlargement of the lateral ventricle is defined as an enlargement of the lateral ventricle without ventricular asymmetry; physiologic variants of mild enlargements of lateral ventricles according to the criteria given in Materials and Methods are coded “0”.