Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage

Table 21

Analysis of the combined effects of TLR9 and IL-8 SNPs on the risk of miscarriage with multiple logistic regression.

	Estimate	Std. error	z value	Pr (>|z|)
(Intercept)	1.7918	0.7638	2.346	0.018978
TLR9 GG + IL-8 CC	−2.4277	0.8679	−2.797	0.005154
TLR9 AA + IL-8 CC	−0.1178	0.9895	−0.119	0.905252
TLR9 GA + IL-8 CC	−2.3979	0.9170	−2.615	0.008925
TLR9 GG + IL-8 CT	−2.1432	0.8204	−2.612	0.008990
TLR9 AA + IL-8 CT	16.7743	1684.1382	0.010	0.992053
TLR9 GA + IL-8 CT	0.5108	1.0646	0.480	0.631343
TLR9 GG + IL-8 TT	−3.5835	1.0801	−3.318	0.000908
TLR9 AA + IL-8 TT	16.7743	2465.3258	0.007	0.994571

Significance codes: 0 ‘’ 0.001 ‘’ 0.01 ‘’ 0.05 ‘.’ 0.1 ‘ ’ 1.